E1 back-to-back connection is working fine. You need to set 
Signaling Mode = NONE, 
Switch type = CAS, 
Framing = 2DS,
and then change the channels mode from switched to nailed and add the group number to each channel (that number represents this specific connection)

We have tried Frame Relay with V.35 and is working fine with no compatibility constraints.

Best Regards,
Ahmed El-Hakim

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