I've had good luck with dist-upgrades the last few times I've done them.
 The one lesson I learned is to not deploy services running over the system
perl, ruby, etc...  I use homebrew and rvm to provision perl/ruby to
services.  That way I don't have to deal with modules getting yanked out
from under me when they rev perl.  I do run over the system mysql, but that
generally has never been a big problem.

-Rob
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